Čes-slov Pediat 2025, 80(90):32-34 | DOI: 10.55095/CSPediatrie2025/049
It's not always just anorexia nervosa
- Dětské oddělení, Oblastní nemocnice Mladá Boleslav
An 18-year-old girl was referred by a psychiatrist to pediatric department for examination due to weight loss and for objectifying her condition.
The girl was already known to have celiac disease and hyperthyroidism due to autoimmune thyroid disease. Clear signs of advanced diabetic ketoacidosis were already present upon admission. The examination also considered other serious conditions, particularly Addison's disease or relapse of thyrotoxicosis.
However, she apparently newly manifested type 1 diabetes mellitus with blood glucose 28.5 mmol/l, HbA1c 122 mmol/mol, and pH 6.985. The girl is now on an intensified insulin regimen and remains under the care of the diabetes and endocrine outpatient clinic. The discussion is focused on differential diagnosis of weight loss, and on associated autoimmune conditions.
Keywords: weight loss, associated autoimmune conditions, diabetic ketoacidosis
Accepted: September 23, 2025; Published: September 1, 2025 Show citation
References
- . World Health Organization. Child Growth Standards. Geneva: WHO 2006.
- . National Institute for Health and Care Excellence (NICE). Faltering growth: recognition and management in children. NG75 2017.
- . Lebl J, Al Taji E, Koloušková S, et al. Dětská endokrinologie a diabetologie. 1. vyd. Praha: Galén 2016.
- . Lebl J, Bronský J, Pohunek P, et al. Diferenciální diagnostika v pediatrii. 2.vyd. Praha: Galén 2014.
- . Lee JM, et al. Endocrine causes of weight loss in children: differential diagnosis and approach. J Pediatr Endocrinol Metab 2020; 33(5): 561-568.
- . Kohout P, et al. Klinická výživa. 1. vyd. Praha: Galén 2021.
- . Binns HJ, et al. Clinical report: Identification and evaluation of children with developmental-behavioral problems. Pediatrics 2007; 120(5): e1285-e1302.
- . Corkins MR, et al. Malnutrition diagnoses in hospitalized children: United States, 2010. JPEN 2016; 40(3): 392-398.
- . https://www.uptodate.com/contents/evaluation-of-weight-loss-in-infants-over-six-months-of-age-children-and-adolescents/abstract/
- . https://publications.aap.org/pediatriccare
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