JOURNAL OF THE CZECH PEDIATRIC SOCIETY AND THE SLOVAK PEDIATRIC SOCIETY

Čes-slov Pediat 2026, 81(5):243-246 | DOI: 10.55095/CSPediatrie2026/038

Cough and cold medications in children: why is it necessary to raise awareness about their proper use?

Jan David1, Patrik Konopásek1, Ľuboš Bača2, Eva Fürstová2
1 Klinika dětí a dorostu, 3. lékařská fakulta, Univerzita Karlova a Fakultní nemocnice Královské Vinohrady, Praha
2 Pediatrická klinika, 1. lékařská fakulta, Univerzita Karlova a Fakultní Thomayerova nemocnice, Praha

Cough and cold medications have long been among the most frequently used over-the-counter and prescription medicinal products in the paediatric population. Numerous international authorities have highlighted the inappropriateness of their use, particularly in children during the first years of life. Nevertheless, these medications remain a

common component of both lay self-medication and professional medical practice. The aim of this article is to provide a concise overview of current evidence and to emphasize the need for systematic education of the Czech medical community regarding the efficacy and safety of this controversial class of medication.

Keywords: cough and cold medications, paediatric population, indication, contraindication, Choosing Wisely

Accepted: July 28, 2026; Published: July 1, 2026  Show citation

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David J, Konopásek P, Bača Ľ, Fürstová E. Cough and cold medications in children: why is it necessary to raise awareness about their proper use? Ces-slov Pediat. 2026;81(5):243-246. doi: 10.55095/CSPediatrie2026/038.
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    References

    1. Eckel N, Sarganas G, Wolf IK, Knopf H. Pharmacoepidemiology of common colds and upper respiratory tract infections in children and adolescents in Germany. BMC Pharmacol Toxicol 2014; 15: 44. Go to original source... Go to PubMed...
    2. Du Y, Knopf H. Self-medication among children and adolescents in Germany: results of the national health survey for children and adolescents (KiGGS). Br J Clin Pharmacol 2009; 68: 599-608. Go to original source...
    3. Schaefer MK, Shehab N, Cohen AL, Budnitz DS. Adverse events from cough and cold medications in children. Pediatrics 2008; 121: 783-787. Go to original source... Go to PubMed...
    4. Medicines and Healthcare products Regulatory Agency, Commission on Human Medicines. Over-the-counter cough and cold medicines for children. Drug Safety Update 2009; 2: 8-9. Go to original source... Go to PubMed...
    5. Berlin J, McCarver-May DG, Notterman DA, et al. Use of codeine- and dextromethorphan-containing cough remedies in children. Pediatrics 1997; 99: 918-920. Go to original source...
    6. Minister of Public Works and Government Services Canada. Nonprescription Oral Paediatric Cough and Cold Labelling Standard, 2009. Dostupné na: https://www.canada.ca/content/dam/hc-sc/migration/hc-sc/dhp-mps/alt_formats/hpfb-dgpsa/pdf/prodpharma/pedlscc_pednecr-eng.pdf [cit. 2025-11-20].
    7. Kivistö JE, Poutanen R, Protudjer JLP, et al. Current Care Guidelines had no immediate effects on antitussive prescriptions to Finnish children. Acta Paediatr 2021; 110: 2445-2447. Go to original source... Go to PubMed...
    8. Smith SM, Schroeder K, Fahey T. Over-the-counter (OTC) medications for acute cough in children and adults in community settings. Cochrane Database Syst Rev 2014; 2014(11): CD001831. Go to original source... Go to PubMed...
    9. Dart RC, Paul IM, Bond GR, et al. Pediatric fatalities associated with over the counter (nonprescription) cough and cold medications. Ann Emerg Med 2009; 53(4): 411-417. Go to original source... Go to PubMed...
    10. American Academy of Pediatrics. Common cold, 2023. Dostupné na: www.publications.aap.org/pediatriccare/article-abstract/doi/10.1542/aap.ppcqr.396147/1495/Common-Cold?redirectedFrom=fulltext.
    11. Česká pediatrická společnost ČLS JEP. Mukolytika pro děti v prvních dvou letech života, 2018. Dostupné na: https://www.pediatrics.cz/pro-odborniky/stanoviska-cps-a-doporuceni/.
    12. Konopásek P, Kotíková K, Pecková M, et al. High prevalence of cough and common cold medication intoxications in the Czech paediatric population. Klin Padiatr 2025. Go to original source...
    13. Hampton LM, Nguyen DB, Edwards JR, Budnitz DS. Cough and cold medication adverse events after market withdrawal and labeling revision. Pediatrics 2013; 132: 1047-1054. Go to original source... Go to PubMed...
    14. Food and Drug Administration. Recommendation against the use of CCM, 2008. Dostupné na: www.fda.gov.
    15. Vassilev ZP, Kabadi S, Villa R. Safety and efficacy of over-the-counter cough and cold medicines for use in children. Expert Opin Drug Saf 2010; 9: 233-242. Go to original source... Go to PubMed...
    16. Csonka P, Nurminen F, Lauhkonen E, et al. Cough medicine prescriptions for children by physician specialty and healthcare sector: a Finnish population-based nationwide register study. Eur J Pediatr 2025; 184: 471. Go to original source... Go to PubMed...
    17. Státní zdravotní ústav ČR. Výskyt akutních respiračních infekcí a chřipky v ČR, 2024. Dostupné na: www.szu.cz/publikaceszu/data/akutni-respiracni-infekce-chripka.
    18. Bača L, Fürstová E, Pecková M, et al. Low awareness of proper use of cold and cough medication among Czech paediatricians: a questionnaire study. Eur J Pediatr 2026. V tisku. Go to original source...
    19. Csonka P, Heikkilä P, Koskela S, et al. Cough and cold medicine prescription rates can be significantly reduced by active intervention. Eur J Pediatr 2022; 181: 1531-1539. Go to original source... Go to PubMed...
    20. OˇFarrell HE, McElrea ER, Chang AB, et al. Mucolytics for children with chronic suppurative lung disease. Cochrane Database Syst Rev 2025; 3(3): CD015313.
    21. European Academy of Pediatrics. Choosing Wisely. Dostupné na: https://eapaediatrics.eu/wp-content/uploads/2025/12/R1-Cough-Medication_Postcard-EN.pdf.
    22. Evropská pediatrická akademie. Choosing Wisely - český překlad. Dostup né na: https://www.pediatrics.cz/content/uploads/2025/11/r1-cough-medication_postcard-czech-translation-pdf.pdf.
    23. Palmu S, Heikkilä P, Kivistö JE, et al. Cough medicine prescriptions for children were significantly reduced by a systematic intervention that reinforced national recommendations. Acta Paediatr 2022; 111: 1248-1249. Go to original source... Go to PubMed...
    24. Goldman RD; Canadian Paediatric Society, Drug Therapy and Hazardous Substances Committee. Treating cough and cold: guidance for caregivers of children and youth. Paediatr Child Health 2011; 16(9): 564-569. Go to original source... Go to PubMed...

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