Čes-slov Pediat 2026, 81(3):158-162 | DOI: 10.55095/CSPediatrie2026/029

A rare complication of an even rarer disease

Paulína Činčilová¹, Susanna Bodnárová¹, Petra Gkalpakioti², Zdeněk Čada³, Zuzana Balogová³, Jana Lhotská¹, Jan David¹¹Klinika dětí, dorostu, 3. lékařská fakulta, Univerzita Karlova, Fakultní nemocnice Královské Vinohrady, Praha

² Dermatovenerologická klinika, 3. lékařská fakulta, Univerzita Karlova a Fakultní nemocnice Královské Vinohrady, Praha

³ Klinika ušní, nosní a krční, 2. lékařská fakulta, Univerzita Karlova a Fakultní nemocnice Motol a Homolka Praha

Keratitis-ichthyosis-

deafness (KID) syndrome is a rare genetically determined disorder characterized primarily by cutaneous and sensory abnormalities. However, affected patients also have a lifelong increased risk of infectious and neoplastic complications involving the skin and mucous membranes. In this case report, we present an eleven-year-old boy with KID syndrome who was hospitalized for suspected acute glossitis

Clinically, a large, palpably mass of the tongue with multiple erosive lesions was the dominant finding. The patient was treated with antibiotics; however, progressive enlargement of the lingual swelling raised suspicion of a malignant

etiology. Magnetic resonance imaging revealed an extensive infiltrative lesion of the tongue with central liquefaction and bilateral cervical lymphadenopathy. Unfortunately, histopathological examination of the biopsy confirmed an unfavorable



diagnosis: This case highlights not only the complexity of KID syndrome and the necessity of long-term follow-up, but also the importance of multidisciplinary management, particularly in patients with rare diseases.

Keywords: KID syndrome, keratitis, ichthyosis, deafness, glossitis, tongue carcinoma

Accepted: April 8, 2026; Published: July 1, 2026  Show citation